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ORBIMED ADVISORS LLC

13F
ORBIMED ADVISORS LLC
Last update 2025-07-02 111 Stocks (11 new)
Value $4.20 Bil Turnover 12 %
Countries:

ORBIMED ADVISORS LLC Profile

Orbimed Advisors is an investment company that was founded in 1989 with a vision to “invest across the spectrum of healthcare companies from venture capital start-ups to large multinational companies.” The company started with its first public equity fund in 1989 and would expand to offer long/short equity and private equity investments by 1993. The company would continue to grow and expand, opening its Mumbai and Shanghai offices in Asia in 2007 and beginning its international expansion. In 2010, Orbimed Advisors would expand to the Middle East, opening an office in Israel. The company would then launch its first health care royalties and credit opportunities fund in 2011 and another royalty opportunities fund in 2015. Orbimed Advisors currently has approximately $15 billion in total assets under management spread across 5 accounts, all of which are discretionary. While its number of accounts has remained relatively steady in recent years, its total assets under management has increased significantly, growing from $1.2 billion back in 2010 to over 10 times that amount today.
ORBIMED ADVISORS LLC Top Holdings of 2025-03-31 View Full List
Ticker
Company
Shares
Value ($1000)
Shares Change %
Weighting %
Trade Impact %
% of Shares outstanding
3M Change %
YTD Change %
Market Cap $Mil
Industry
SVA
Sinovac Biotech Ltd
2,718,735
333,996.6
0%
7.960
0%
3.780
-113.33%
-113.33%
460.3
Biotechnology
EWTX
Edgewise Therapeutics Inc
15,021,721
330,477.9
0%
7.880
0%
14.280
-2.97%
-46.10%
1,513.8
Biotechnology
BSX
Boston Scientific Corp
2,813,200
283,795.6
-10.98%
6.770
-0.64%
0.190
+8.94%
+20.64%
159,425.1
Medical Devices & Instruments
LLY
Eli Lilly and Co
337,600
278,827.2
0%
6.650
0%
0.040
-3.48%
+3.87%
717,192.0
Drug Manufacturers
ELVN
Enliven Therapeutics Inc
7,959,538
156,643.7
0%
3.730
0%
16.220
+25.77%
-0.67%
1,318.4
Biotechnology
ISRG
Intuitive Surgical Inc
291,000
144,123.6
-27.56%
3.440
-1.19%
0.080
+2.87%
-3.83%
179,937.3
Medical Devices & Instruments
SYK
Stryker Corp
359,200
133,712.2
+4.30%
3.190
+0.13%
0.090
+12.51%
+11.85%
153,221.4
Medical Devices & Instruments
ARGX
argenx SE
206,700
122,338.5
+8.96%
2.920
+0.24%
0.340
-3.23%
-6.44%
35,093.0
Biotechnology
EW
Edwards Lifesciences Corp
1,532,000
111,039.4
+33.76%
2.650
+0.67%
0.260
+9.15%
+3.89%
45,115.4
Medical Devices & Instruments
UNH
UnitedHealth Group Inc
201,200
105,378.5
+53.71%
2.510
+0.88%
0.020
-31.16%
-41.52%
265,347.7
Healthcare Plans

ORBIMED ADVISORS LLC's Historical Top Holdings Breakdowns

ORBIMED ADVISORS LLC's Top Stock Picks View Full List
Ticker
Company
Date
Action
Impact %
Price Range
Price
Price Change from Avrg%
Comment
Current Shares
Share Change
SRPT
Sarepta Therapeutics Inc
2025-03-31
Sold Out
Sold Out
-2.41%
â—Ź
63.82 ($105.27) 127.89
$13.32
-87.35%
Sold Out
0
-963,400
PFE
Pfizer Inc
2025-03-31
New Buy
New Buy
+2.33%
â—Ź
25.01 ($26.17) 27.13
$25.36
-3.10%
New holding
3,850,200
3,850,200
MRK
Merck & Co Inc
2025-03-31
Sold Out
Sold Out
-1.70%
â—Ź
83.01 ($93.37) 101.02
$83.98
-10.06%
Sold Out
0
-829,900
BIIB
Biogen Inc
2025-03-31
Sold Out
Sold Out
-1.60%
â—Ź
133.43 ($142.96) 153.27
$130.98
-8.38%
Sold Out
0
-509,100
ISRG
Intuitive Surgical Inc
2025-03-31
Reduce
Reduce
-1.19%
â—Ź
476.78 ($553.02) 610.45
$501.95
-9.23%
Reduce -27.56%
291,000
-110,700
AXSM
Axsome Therapeutics Inc
2025-03-31
New Buy
New Buy
+1.08%
â—Ź
80.05 ($113.93) 137.75
$106.36
-6.64%
New holding
386,700
386,700
UHS
Universal Health Services Inc
2025-03-31
Sold Out
Sold Out
-0.99%
â—Ź
163.99 ($182.38) 193.27
$164.82
-9.63%
Sold Out
0
-269,300
SION
Sionna Therapeutics Inc
2025-03-31
New Buy
New Buy
+0.92%
â—Ź
0 ($15.65) 22.24
$19.77
26.33%
New holding
3,704,959
3,704,959
UNH
UnitedHealth Group Inc
2025-03-31
Add
Add
+0.88%
â—Ź
461.52 ($511.2) 548.18
$292.51
-42.78%
Add 53.71%
201,200
70,300
THC
Tenet Healthcare Corp
2025-03-31
Reduce
Reduce
-0.85%
â—Ź
119.51 ($131.69) 144.98
$158.31
20.21%
Reduce -41.29%
465,000
-327,000

ORBIMED ADVISORS LLC Total Holding History ($B)

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ORBIMED ADVISORS LLC's Asset Allocation

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ORBIMED ADVISORS LLC Past Portfolios

Portfolio Date Number of Stocks New Stocks Total Value ($Mil) Q/Q Turnover

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ORBIMED ADVISORS LLC's Hypothetical Growth since 2025-03-31

ORBIMED ADVISORS LLC's Yearly Returns

Year Portfolio % % Excess Gain %

ORBIMED ADVISORS LLC's Holdings Heat Map

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